Top 10 Pharma API Manufacturers in India

Active Pharmaceutical Ingredients (APIs) are the primary components in pharmaceutical drugs that produce their intended effects. These substances are biologically active and play a critical role in therapeutic treatments. 

In India, API manufacturing is a key sector within the pharmaceutical industry. Indian companies are renowned for their expertise in producing high-quality APIs at competitive prices, which are then used by pharmaceutical companies worldwide to formulate finished medicines.

In this article, we explore the top 10 API manufacturers in India, highlighting their contributions to the global healthcare industry. These companies play a pivotal role in supplying crucial ingredients for pharmaceutical formulations worldwide, adhering to stringent regulatory standards and fostering continuous advancements in drug development. 

List of Top 10 Pharma API Manufacturers in India

Before exploring the top 10 API manufacturers in India, let’s look at some quick facts about APIs.

• Active Pharmaceutical Ingredients (APIs) are essential components of the pharmaceutical industry, with India producing over 40% of the world’s generic APIs.
• The Indian API market is valued at approximately USD 11 billion and is projected to grow significantly in the coming years. 
• Indian API manufacturers meet nearly 20% of the global demand, serving diverse therapeutic areas. This substantial production capacity positions India as a vital player in the global pharmaceutical supply chain.

1.Sun Pharmaceutical Industries Ltd.

Sun Pharmaceutical Industries Ltd., founded in 1983, is India’s largest pharmaceutical company and the fourth largest generic pharmaceutical company worldwide. With a global revenue of $5.4 billion and over 41,000 employees across the globe, Sun Pharma has a strong presence in over 100 countries. 

The company boasts a diverse portfolio of high-quality APIs catering to various therapeutic areas, including cardiology, psychiatry, neurology, and oncology. Its state-of-the-art manufacturing facilities adhere to stringent regulatory standards, ensuring the production of safe and effective APIs. Sun Pharma’s commitment to innovation and quality has solidified its position as a trusted name in the pharmaceutical industry. Their API’s includes:

• Abaloparatide
• Abiraterone Acetate
• Acalabrutinib
• Acotiamide
• Afatinib Dimaleate
• Bempedoic Acid
• Canagliflozin
• Dabigatran Etexilate
• Eluxadoline
• Faropenem Na

Contact them – Sun Pharma Advanced Research Centre (SPARC), Tandalja, Vadodara – 390012, Gujarat, INDIA.
For more info:https://bulkdrugsdirectory.com/api/sun-pharmaceutical-industries-ltd/

2.Cipla Limited

Cipla Limited, established in 1935, is a leading API manufacturers in India known for its commitment to high-quality, affordable healthcare. With a global revenue of $2.4 billion and a workforce of over 25,000 employees, Cipla has a strong presence in more than 80 countries. The company’s extensive API portfolio addresses a wide range of therapeutic areas, including respiratory, oncology, cardiovascular, and anti-retroviral segments. 

Cipla has been recognized with numerous awards, including the KPMG India ESG Excellence Awards ‘23 for ESG Champion Award – Pharmaceutical & Healthcare category, and several accolades at the India Health & Wellness Awards ‘23: Silver in Patient Centric Brand in Cancer Care for “Unfold the Happiness” (Oncology), Silver in Disease Screening Initiative of the Year for “Acidity Score Clinic” (GERD), and Silver in Disease Screening Initiative of the Year for “Gaas Baas Kapas Ra Saas” (Cipla Nepal). The company’s commitment to innovation and patient-centric healthcare solutions has solidified Cipla as a respected leader in the global pharmaceutical industry. Their APIs includes:

• Abacavir Sulphate
• Albendazole
• Bicalutamide
• Carboplatin
• Danazol
• Efavirenz
• Felodipine
• Flutamide
• Gefitinib
• Lansoprazole

Contact them – Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

For more info: https://bulkdrugsdirectory.com/api/cipla-limited/ 

3. Aurobindo Pharma Limited

Founded in 1986, Aurobindo Pharma Limited has grown into a prominent global pharmaceutical company with a workforce of over 24,000 employees worldwide. The company operates 27 state-of-the-art manufacturing and packaging facilities globally, approved by leading regulatory bodies such as US FDA, UK MHRA, TGA Australia, MCC-SA, EMA, and ANVISA for both APIs and formulations. Aurobindo Pharma boasts a robust portfolio, with over 650 ANDAs filed and 450+ final approvals. 

It manufactures more than 40 billion dosage forms annually and employs 1,700 expert scientists and analysts globally. Over 90% of its revenues come from exports to over 150 countries, underscoring its strong international presence and commitment to delivering high-quality pharmaceutical products globally. Their APIs includes:

• Abacavir
• Amoxicillin
• Amlodipine
• Alendronic acid
• Alprazolam
• Ambroxol 
• Aripiprazole
• Atorvastatin
• Diltiazem
• Glimepiride 

Contact them – Aurobindo Pharma Limited, Plot no. 2, Maitrivihar, Ameerpet, Hyderabad-500038 Telangana, India.

For more info: https://bulkdrugsdirectory.com/api/aurobindo-pharma-ltd/ 

4. Divi’s Laboratories Limited

Established in the year 1990, Divis Laboratories Limited has grown to become a leading manufacturer of Active Pharmaceutical Ingredients (APIs), supplying high-quality products to over 95 countries worldwide. With 31 years of experience in the industry, Divi’s operates three R&D centers and three manufacturing units dedicated to generic APIs, nutraceutical ingredients, and custom synthesis of APIs for major pharmaceutical companies. The company employs 17,000 professionals, including approximately 400 scientists, who collaborate across departments to deliver world-class products.

Divi’s Laboratories is a public limited company listed on the Indian stock exchange, with a revenue of approximately $1.2 billion for the fiscal year 2021-22. The company’s advanced manufacturing facilities are integral to its operations, ensuring stringent quality control and compliance with global regulatory standards. Their APIs includes:

• Bupropion HCl
• Capecitabine
• Carbidopa
• Diltiazem HCl
• Dextromethorphan Base
• Dextromethorphan HBr
• Gabapentin
• Iopamidol
• Iohexol
• Irbesartan
• Lacosamide

Contact them – 1-72/23(P)/DIVIS/303, Divi Towers, Cyber Hills, Gachibowli, Hyderabad,Telangana, India – 500 032.

For more info: https://bulkdrugsdirectory.com/api/divis-pharmaceuticals-pvt-ltd/  

5. Lupin Limited

Lupin Limited, one of the top 10 API manufacturers in India, with over 20,000 employees and a diverse portfolio of more than 1,000 products, has established a strong global presence in over 100 countries. The company operates 15 global facilities and seven R&D centers, underscoring its commitment to innovation and quality. Lupin’s supply chain team was recognized with the Best Integrated Business Strategy of the Year Award, and the Pithampur team won two Gold Awards at the 20th Edition of CII National Circle Competition. Additionally, Lupin received national awards for manufacturing competitiveness for its Pithampur and Sikkim facilities. In 2024, Lupin’s HUMRAHI initiative was honored as the Patient-Centric Pharmaceutical Company of the Year.

Lupin’s extensive global manufacturing footprint ensures the delivery of quality-assured products to customers worldwide. The company’s strategic investments in manufacturing capital aim to create affordable, high-quality medicines that address unmet patient needs. As part of its growth strategy, Lupin continues to enhance capacities and automation to support its pipeline of complex generics and biotechnology products. Their APIs includes:

• Cefaclor
• Cefadroxil
• Cephalexin
• Desvenlafaxine Succinate/Benzoate
• Ethambutol
• Ezetimibe
• Levetiracetam
• Pyrazinamide
• Rifabutin
• Rifaximin

Contact them – Lupin Limited, 3rd Floor, Kalpataru Inspire, Off. Western Expressway Highway, Santacruz (East), Mumbai 400 055, India.

For more info: https://bulkdrugsdirectory.com/api/lupin-limited/ 

Also Read: Top 20 Pharma API Manufacturers in India

6. Glenmark Pharmaceuticals Limited

Glenmark Pharmaceuticals Limited is a research-led, global pharmaceutical company with a strong presence in branded, generics, and OTC segments, focusing on respiratory, dermatology, and oncology therapies. With over 15,000 employees worldwide, including 1,400+ in R&D, the company operates four state-of-the-art research and development centers and ten world-class manufacturing facilities across five continents. Glenmark’s commercial presence spans over 80 countries, with more than 60% of its revenue derived from international markets.

Ranked among the world’s top 100 biopharmaceutical companies and the top 50 generics and biosimilars companies, Glenmark is dedicated to innovation and advancing medical treatment. The company is committed to developing novel chemical and biological entities and creating specialty products, such as RYALTRIS®, to address gaps in treatment. Their APIs includes:

• Adapalene
• Alogliptin
• Amiodarone
• Apixaban
• Apremilast
• Aprepitant
• Arformoterol
• Atovaquone
• Azelaic Acid
• Bosentan
• Bupropion HCl
• Butenafine HC
• Canagliflozin
• Cilazapril
• Cilostazol
• Colistimethate Na
• Dabigatran

Contact them – Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

For more info: https://bulkdrugsdirectory.com/api/glenmark-pharmaceuticals-limited/ 

7. Novartis AG

Novartis AG is a leading global healthcare company headquartered in Basel, Switzerland, with a strong presence in India. Known for its innovative medicines and cutting-edge research, Novartis focuses on several therapeutic areas, including oncology, cardiology, immunology, and neurosciences. The company employs over 108,000 people worldwide and operates in more than 140 countries, ensuring a vast reach of its healthcare solutions.Novartis is at the forefront of pharmaceutical innovation, with a robust pipeline of new medicines and therapies. The company invests significantly in research and development, operating multiple R&D centers and collaborating with institutions and biotech firms to advance medical science. 

In India, Novartis is involved in the manufacturing of high-quality APIs and formulations, adhering to stringent global standards.The company’s commitment to improving patient lives is reflected in its numerous awards and recognitions, including being named one of the most sustainable companies in the pharmaceutical industry. Novartis continues to drive healthcare forward through its dedication to research, quality, and patient-centric approaches, making it a top API manufacturers in India. Their APIs includes:

• aldesleukin
• alpelisib
• asciminib
• Basiliximab
• benazepril hydrochloride
• Brinzolamide
• brimonidine tartrate
• Brinzolamide
• timolol
• brolucizumab
• Canakinumab

Contact them -Inspire BKC, 7th Floor, Bandra-Kurla Complex, Bandra (East) Mumbai 400051

For more info: 

8. Pfizer Inc.

Pfizer Inc., founded in 1849, is a global pharmaceutical giant headquartered in New York, USA, with a significant presence in India. Known for its groundbreaking research and development, Pfizer focuses on various therapeutic areas, including oncology, immunology, cardiology, and infectious diseases. The company employs over 78,000 people worldwide and operates in more than 125 countries, delivering innovative healthcare solutions to millions.

Pfizer is renowned for its commitment to advancing medical science, demonstrated by its development of the first COVID-19 vaccine in collaboration with BioNTech. The company’s extensive R&D infrastructure includes numerous research centers and partnerships with leading academic institutions and biotech firms, driving the discovery of new treatments and therapies.In India, Pfizer manufactures a wide range of high-quality APIs and finished dosage forms, adhering to stringent global standards. 

The company’s advanced manufacturing facilities ensure the production of safe and effective medicines, contributing significantly to global healthcare. Their APIs includes:

• Adalimumab-afzb
• quinapril HCI
• Adenosine
• Spironolactone
• Ramipril
• Etomidate
• aminophylline
• Ampicillin Sodium
• (atracurium besylate)
• Aztreonam

Contact them – Pfizer Limited, Unit 601-604,6th Floor, Block A, Hyatt Regency Delhi, Bhikaji Cama Place, New Delhi -110066

For more info: https://bulkdrugsdirectory.com/api/pfizer-ltd/ 

9. Teva Pharmaceutical Industries Ltd.

Teva Pharmaceutical Industries Ltd., established in 1901, one of the leading API manufacturers in India, and headquartered in Israel, is a leading global pharmaceutical company with a robust presence in India. Teva offers the world’s largest medicine cabinet, featuring a full spectrum of products from generics and APIs to over-the-counter treatments, specialty, and biologic medicines. The company has a portfolio of more than 3,600 medicines and produces approximately 76 billion tablets and capsules annually.

With over 53 manufacturing facilities in more than 33 countries, Teva ranks among the top pharmaceutical companies globally and operates in 58 markets. The company employs approximately 37,000 people dedicated to providing high-quality, affordable healthcare solutions. Every day, Teva’s innovative medicines serve about 200 million people worldwide.

Teva’s commitment to excellence is reflected in its state-of-the-art manufacturing facilities and continuous investment in research and development. By focusing on quality, affordability, and patient-centric care, Teva remains a leading API manufacturers in India. Their APIs includes:

• Abemaciclib* 
• Abiraterone Acetate 
• Abrocitinib* 
• Acalabrutinib* 
• Adagrasib* 
• Afatinib Dimaleate* 
• Alclometasone Dipropionate 
• Alfacalcidol 
• Allopurinol 
• Amcinonide 
• Amitriptyline Hcl 
• Anastrozole

Contact them – Teva API India Private Limited, Q1- Q4, Industrial Area, Ghirongi,
Malanpur, Dist- Bhind, Madhya Pradesh, Pin-477 117, India

For more info: 

10. Aarti Drugs

Aarti Drugs Ltd., leading API manufacturers in India, established in 1984, is a key player in the $900 million Aarti Group of Industries. The company has a robust R&D division located at Tarapur, Maharashtra Industrial Development Corporation (MIDC), close to its manufacturing sites. Aarti Drugs specializes in the production of Active Pharmaceutical Ingredients (APIs), pharma intermediates, specialty chemicals, and formulations through its wholly-owned subsidiary, Pinnacle Life Science Private Limited.

The company’s API product range includes Ciprofloxacin Hydrochloride, Metronidazole, Metformin HCL, Ketoconazole, and Ofloxacin, while its specialty chemicals portfolio features Benzene Sulphonyl Chloride and Methyl Nicotinate. Over the years, Aarti Drugs has carved a niche for itself and aims to expand its volumes further. With government initiatives to encourage private health insurance schemes, consumer spending on medicines is expected to increase, spurring growth in the domestic generic sector.

Aarti Drugs’ manufacturing units are GMP certified, and the company is in the process of acquiring ISO 9002 compliance for all its units, with one unit already approved. The company is committed to becoming the first choice in the expanding market through better products, quality assurance, and timely delivery. Their APIs includes:

• Aceclofenac
• Celecoxib
• Diclofenac Sodium
• Diclofenac Potassium
• Nimesulide
• Gatifloxacin Sesquihydrate
• Moxifloxacin
• Norfloxacin
• Ofloxacin
• Metronidazole
• Ticlopidine HCL

Contact them – Aarti Drugs Ltd, Mahendra Industrial Estate, Ground Floor, Road No 29, Plot No 109-D, SION (East), MUMBAI- 400 022.( INDIA)

For more info: https://bulkdrugsdirectory.com/api/aarti-drugs-ltd/ 

Conclusion

Listed above are the top 10 pharmaceutical API manufacturers in India. Each of these companies exemplifies the strengths of the Indian pharmaceutical sector, from extensive product portfolios and cutting-edge research to compliance with stringent international regulatory standards.

We trust the list of API manufacturers in India provided here has been helpful to you. Please feel free to choose a company that meets your needs. For more information, visit our website. Our team is ready to assist you further.