Suven Life Sciences Limited

Welcome to Suven Life Sciences Limited

Suven Life Sciences Limited, a pioneering pharmaceutical company with a rich history dating back to its incorporation as Suven Pharmaceuticals Pvt. Ltd. in 1989. Since then, Suven has evolved into a dynamic entity listed on the Bombay Stock Exchange (BSE) and National Stock Exchange (NSE), achieving milestones in drug discovery, development, and global recognition.

Vision and Mission

Suven is on a mission to address unmet medical needs in Mental Health, delivering health for patients and value for partners. The company actively seeks new therapies in the Central Nervous System (CNS) domain, demonstrating its commitment to advancing healthcare solutions.

History

The journey of Suven Life Sciences is marked by significant achievements:

• In 1995, Suven transitioned from a Private Limited Company to a Public Limited Company, listing its shares on BSE and NSE.
• In 2003, the company underwent a name change to Suven Life Sciences Limited.
• Over the years, Suven has received numerous awards and recognitions, including Forbes Asia’s “Best Under A Billion” Award and Pharmexcil’s “Gold Patent Award.

Recent Highlights

In 2020, Suven achieved a key milestone with the NCLT-sanctioned Scheme of Arrangement (demerger), separating its CRAMS Business undertaking. The demerger facilitated a focused approach, with Suven Pharmaceuticals Limited emerging as the resulting company.

Commitment to Excellence

Suven’s commitment to excellence is evident through its continuous pursuit of cutting-edge research and development. The company’s research services encompass a wide spectrum, including behavioral pharmacology, microdialysis, receptor occupancy, electrophysiology, safety pharmacology, and more.

Business Segments

Drug Discovery & Development Support Services (DDDSS)
Suven Life Sciences is at the forefront of providing Drug Discovery and Development Support Services (DDDSS) to global pharmaceutical and biotech companies. With state-of-the-art facilities and a highly qualified team of scientists, Suven excels in Synthetic, Medicinal, and Analytical Chemistry, In-vitro Assay development, Drug Metabolism & Pharmacokinetics, CNS Pharmacology, Toxicology, Bioanalysis, and NCE Formulations.

Synthetic and Medicinal Chemistry
Suven’s Synthetic and Medicinal Chemistry services are designed to align seamlessly with their partners’ goals and expectations.

• Hit to lead generation, meticulously addressing potential IP issues.
• Lead optimization and the selection of clinical development candidates.
• Comprehensive support for scale-up chemistry, utilizing Kilo-lab and a US FDA approved plant.
• Development and/or optimization of synthetic routes.
• Documentation for IND application filing.
• Identification, synthesis, and characterization of metabolites.
• Synthesis of reference standards.
• Conducting crystallization studies, polymorph identification, and control.
• Salt screening and optimal salt selection for enhanced efficacy and stability.

Analytical Chemistry
Suven delivers a comprehensive range of analytical services crucial for supporting drug development, process research, and product release protocols.
Services include:

• • Method development and validation utilizing HPLC, GC/GC-HS.
  • Structure elucidation through NMR.
  • LC-MS/MS analysis.
  • DSC & TGA investigations.
  • Chiral and HPLC Purity assessments.
  • Analysis of Organic Volatile Impurities and Residual Solvents.
  • Conducting stability studies following ICH guidelines and customer specifications.
  • Impurity profiling.
  • Achiral and Chiral Separations using semi-preparative techniques.

Bioanalysis
Suven Life Sciences boasts a cutting-edge bioanalytical laboratory equipped with state-of-the-art and highly sensitive mass spectrometers, seamlessly integrated with UHPLCs. This advanced setup enables swift results and supports various studies with rapid turnaround times, including:

Bioanalysis:
Conducting thorough analysis for a range of substances.

Receptor Occupancy and Biomarker Measurement:
Evaluating the occupancy of receptors and measuring biomarkers with precision.

Bioavailability and Bioequivalence:
Assessing the availability and equivalence of substances in biological systems.

Bioanalysis for Non-Clinical GLP Toxicology Studies:
Providing analytical support for non-clinical studies adhering to GLP standards.

First in Human (FIH) Clinical Trials:
Supporting the initial phases of clinical trials with accurate bioanalytical data.

Target Site Concentrations:
Determining concentrations in various target sites, including systemic, dermal, ocular, brain, dialysates, and tissues.

Metabolite Identification (In vitro, In vivo):
Identifying metabolites through comprehensive analysis, both in vitro and in vivo.

Commitment to Excellence

Suven’s commitment to excellence is evident through its continuous pursuit of cutting-edge research and development. The company’s research services encompass a wide spectrum, including behavioral pharmacology, microdialysis, receptor occupancy, electrophysiology, safety pharmacology, and more.