Camptothecin
CAS NO:7689-03-4 Want to find the best supplier of Camptothecin? Bulkdrugs directory will help you find the best supplier. Browse our list of Camptothecin manufacturers and suppliers to find the best product.-
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Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used in traditional Chinese medicine. It has been used clinically more recently in China for the treatment of gastrointestinal tumors. CPT showed anticancer activity in preliminary clinical trials, especially against breast, ovarian, colon, lung, and stomach cancers.
IUPAC Name:(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
CAS NO:7689-03-4
Synonyms:camptothecin
Camptothecine
7689-03-4
(S)-(+)-Camptothecin
Campathecin
(+)-Camptothecine
d-Camptothecin
20(S)-Camptothecine
(+)-Camptothecin
Molecular Formula:C20H16N2O4
Molecular Weight:348.4 g/mol
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